Search Results - Edelstein, Stuart J

Stuart J. Edelstein

Stuart J. Edelstein (born 1941) is a biophysicist, emeritus professor from the University of Geneva, professeur extraordinaire at the École Normale Supérieure and visiting scientist at the Babraham Institute.

His research focuses on the properties of allosteric proteins, which conformations and activities are affected by the binding of ligands. Using mathematical models and 3D structures, he studied the function of hemoglobin, solving the structure of mutant form leading to sickle-cell disease. He then turned his attention on the allosteric regulation of neurotransmitter receptors, in particular the nicotinic acetylcholine receptors in collaboration with Jean-Pierre Changeux. Provided by Wikipedia