Search Results - "RNA polymerase"

RNA polymerases as molecular motors

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Molecular biology genes to proteins by Tropp, Burton E.

Table of Contents: “…Introduction to molecular biology -- Protein structure -- Protein function -- Nucleic acid structure -- Techniques in molecular biology -- Chromosome structure -- Genetic analysis in molecular biology -- Viruses in molecular biology -- DNA replication in bacteria -- DNA replication in eukaryotes and the archaea -- DNA damage -- DNA repair -- Recombination -- Transposons and other mobile elements -- Bacterial RNA polymerase -- Regulation of bacterial gene transcription -- RNA polymerase II : basal transcription -- RNA polymerase II : regulation -- RNA polymerase II : cotranscriptional and posttranscriptional processes -- RNA polymerases I and III and organellar RNA polymerases -- Regulatory RNAs -- Protein synthesis : the genetic code -- Protein synthesis : the ribosome…”
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Antibiotics targets, mechanisms and resistance

Table of Contents: “…A chemist's survey of different antibiotic classes -- Antibacterial discovery: problems and possibilities -- Impact of microbial natural products on antibacterial drug discovery -- Antibiotics and resistance: a fatal attraction -- Fitness costs of antibiotic resistance -- Inhibitors of cell-wall synthesis -- Inhibitors of bacetrial cell partitioning -- The membrane as a novel target site for antibiotics to kill persisting bacterial pathogens -- Bacterial membrane, a key for controlling drug influx and efflux -- Interference with bacterial cell-to-cell chemical signaling in development of new anti-infectives -- Recent developments in inhibitors of bacterial type IIA topoisomerases -- Antibiotics targeting bacterial RNA polymerase -- Inhibitors targeting riboswitches and ribozymes -- Targeting ribonuclease P -- Involvement of ribosome biogenesis in antibiotic functions, acquired resistance, and future opportunities in drug discovery -- Aminoacyl-tRNA synthetase inhibitors -- Antibiotics targeting translation initiation in prokaryotes -- Inhibitors of bacterial elongation factor EF-Tu -- Aminoglycoside antibiotics: structural decoding of inhibitors targeting the ribosomal decoding A site -- Reptidyltransferase inhibitors of the bacterial ribosome -- Antibiotics inhibiting the translocation step of protein elongation on the ribosome -- Antibiotics at the ribosomal exit tunnel--selected structual aspects -- Targeting HSP70 to fight cancer and bad bugs: one and the same battle?…”
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