Search Results - "Disease Models

  1. 101

    The mouse in biomedical research

    Published 2007
    Table of Contents: “…History, wild mice and genetics --v. 2. Diseases -- v. 3. Normative biology, husbandry, and models -- v. 4. …”
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  19. 119

    Human molecular genetics by Strachan, T., Read, Andrew P.

    Published 2019
    Table of Contents: “…Pt. 1: Basics of DNA, chromosomes, cells, development and inheritance -- Basic principles of nucleic acid structure and gene expression -- Fundamentals of cells and chromosomes -- Fundamentals of cell-cell interactions and immune system biology -- Aspects of early mammalian development, cell differentiation, and stem cells -- Patterns of inheritance -- Pt. 2: Understanding genomes -- Core DNA technologies: amplifying DNA, nucleic acid hybridization, and DNA sequencing -- Analyzing the structure and expression of genes and genomes -- Principles of genetic manipulation of mammalian cells -- Uncovering the architecture and workings of the human genome -- Gene regulation and the epigenome -- Pt. 3: Genetic variation between individuals and species -- An overview of human genetic variation -- Human population genetics -- Comparative genomics and genome evolution -- Human evolution -- Pt. 4: Human genetic disease -- Chromosomal abnormalities and structural variants -- Moleculars pathology: connecting phenotypes to genotypes -- Mapping and identifying genes for monogenic disorders -- Complex disease identifying susceptibility factors and understanding pathogenesis -- Cancer genetics and genomics -- Pt. 5: Applied human molecular genetics -- Genetic testing in healthcare and the law -- Model organisms and modeling disease -- Genetic approaches to treating disease.…”
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