Bioinformatics Methods and Applications

• Other Authors: Dev Bukhsh Singh (Editor), Rajesh Kumar Pathak (Editor)
• Format: Book
• Language: English
• Published: Oxford, United Kingdom Elsevier 2022
• Subjects: Computational Biology > methods; Medical Informatics Computing
• Online Access: Click Here to View Status and Holdings.

Bioinformatics: Methods and Applications provides a thorough and detailed description of principles, methods, and applications of bioinformatics in different areas of life sciences. It presents a compendium of many important topics of current advanced research and basic principles/approaches easily...

Table of Contents:

• Content: List of contributors - Preface - 1. Introduction to basics of bioinformatics - 2. Biological databases and their application - 3. Biological sequence analysis - 4. Genome assembly and annotation - 5. Computational molecular phylogeny: concepts and applications - 6. Applications and challenges of microarray and RNA-sequencing - 7. RNA-seq for revealing the function of the transcriptome - 8. Analysis of SSR and SNP markers - 9. Gene ontology: application and importance in functional annotation of the genomic data - 10. Metagenomics: the boon for microbial world knowledge and current challenges - 11. Protein structure prediction - 12. Structural and functional analysis of protein - 13. Computational approaches in drug designing - 14. Structure-based drug designing - 15. Ligand-based drug designing - 16. Discovery and optimization of lead molecules in drug designing - 17. Pharmacophore modeling and its applications - 18. Molecular docking and molecular dynamics simulation - 19. Pharmacokinetics and pharmacodynamics analysis of drug candidates - 20. Computational approaches for vaccine designing - 21. Metabolomics and flux balance analysis - 22. Topological parameters, patterns, and motifs in biological networks - 23. Network biology and applications - 24. Pathway modeling and simulation analysis - 25. Systems biology and big data analytics - 26. Machine learning in bioinformatics - 27. Bioinformatics and biological data mining - Index