Animal Models in Cancer Drug Discovery

• Other Authors: Asfar Azmi (Editor), Ramzi M. Mohammad (Editor)
• Format: Book
• Language: English
• Published: San Diego, United States Academic Press 2019
• Subjects: Antineoplastic Agents; Drug Discovery; Models, Animal
• Online Access: Click Here to View Status and Holdings.

Animal Models in Cancer Drug Discovery brings forward the most cutting-edge developments in tumor model systems for translational cancer research. The reader can find under this one volume virtually all types of existing and emerging tumor models in use by the research community. This book provides...

Table of Contents:

• Chapter 1 Role of animal research in human malignancies - Chapter 2 Preclinical models in ovarian cancer - Chapter 3 Animal models of cancer-associated cachexia - Chapter 4 Imaging tools to enhance animal tumor models for cancer research and drug discovery - Chapter 5 Protocols in genetic mice models of pancreatic cancer - Chapter 6 Chemo-prevention and interception of obesity-promoted pancreatic ductal adenocarcinoma - Chapter 7 Animal models of primary brain tumors - Chapter 8 Metastatic brain tumor models and drug brain penetration analysis - Chapter 9 A guide to tumor assessment methodologies in cancer drug discovery - Chapter 10 Mouse models of pancreatic cancer: An ever-emerging arm of cancer drug discovery - Chapter 11 Mouse models of gastrointestinal cancers in drug development and research - Chapter 12 Preclinical animal tumor models to study prevention of colon cancer recurrence by curcumin - Chapter 13 Role of 3D tissue engineering models for human cancer and drug development - Chapter 14 Drug development using pancreatic and lung organoid models - Chapter 15 Leveraging dogs with spontaneous cancer to advance drug development - Chapter 16 Cancer imaging in preclinical models - Chapter 17 Animal (mouse) models of melanoma - Chapter 18 Animal mouse models of acute myeloid leukemia