Fusion Genes and Cancer

Development of cancer, a dreadful disease of mankind, is a multi-stage process involving numerous molecular alterations at both genomic and proteomic levels. Immense research for the past several decades in the field of cancer identified many such mutations and their role in carcinogenesis. Concept...

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Other Authors: Kunnumakkara, Ajaikumar B. (Editor), Padmavathi, Ganesan (Editor), Roy, Nand Kishor (Editor)
Format: Book
Language:English
Published: New Jersey World Scientific 2017
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Online Access:Click Here to View Status and Holdings.
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245 0 0 |a Fusion Genes and Cancer  |c editors, Ajaikumar B. Kunnumakkara, Ganesan Padmavathi, Nand Kishor Roy, Indian Institute of Technology (IIT) Guwahati, India 
264 # 1 |a New Jersey  |b World Scientific  |c 2017 
264 # 4 |c ©2017 
300 # # |a xviii, 414 pages  |b color illustrations  |c 24 cm 
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504 # # |a Includes bibliographical references and index 
520 # # |a Development of cancer, a dreadful disease of mankind, is a multi-stage process involving numerous molecular alterations at both genomic and proteomic levels. Immense research for the past several decades in the field of cancer identified many such mutations and their role in carcinogenesis. Concept of 'fusion genes' seeded way back in 20th century has now grown into a new field of cancer research. However, there is a lack of knowledge among scientists about these fusion genes and their importance in cancer, which can be mainly attributed to unavailability of a comprehensive book on this topic. Therefore, this book is first of its kind and aims at giving a detailed idea on the formation of gene fusions and their importance in the development and progression of cancer; techniques to identify novel gene fusions; and therapeutics available to target various fusion proteins and their impact in cancer therapy by compiling the information from the literature available till date 
650 # 2 |a Gene Fusion 
650 # 2 |a Neoplasms  |x genetics 
700 1 # |a Kunnumakkara, Ajaikumar B.  |e editor 
700 1 # |a Padmavathi, Ganesan  |e editor 
700 1 # |a Roy, Nand Kishor  |e editor 
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