Targeted Biomarker Quantitation by LC-MS

The demand among scientists and clinicians for targeted quantitation experiments has experienced explosive growth in recent years. While there are a few books dedicated to bioanalysis and biomarkers in general, until now there were none devoted exclusively to addressing critical issues surrounding t...

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Bibliographic Details
Other Authors: Weng, Naidong (Editor), Jian, Wenying (Editor)
Format: Book
Language:English
Published: Hoboken, NJ WILEY 2017
Series:Wiley series on pharmaceutical science and biotechnology. Practices, applications, and methods
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Online Access:Click Here to View Status and Holdings.
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245 0 0 |a Targeted Biomarker Quantitation by LC-MS  |c Edited by Dr. Naidong Weng and Dr. Wenying Jian 
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504 # # |a Includes bibliographical references and index 
520 # # |a The demand among scientists and clinicians for targeted quantitation experiments has experienced explosive growth in recent years. While there are a few books dedicated to bioanalysis and biomarkers in general, until now there were none devoted exclusively to addressing critical issues surrounding this area of intense research. Target Biomarker Quantitation by LC-MS provides a detailed blueprint for quantifying biomarkers in biological systems. It uses numerous real-world cases to exemplify key concepts, all of which were carefully selected and presented so as to allow the concepts they embody to be easily expanded to future applications, including new biomarker development. Target Biomarker Quantitation by LC-MS primarily focuses on the assay establishment for biomarker quantitation-a critical issue rarely treated in depth. It offers comprehensive coverage of three core areas of biomarker assay establishment: the relationship between the measured biomarkers and their intended usage; contemporary regulatory requirements for biomarker assays (a thorough understanding of which is essential to producing a successful and defendable submission); and the technical challenges of analyzing biomarkers produced inside a living organism or cell. 
650 # 0 |a Liquid chromatography 
650 # 0 |a Mass spectrometry 
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