Basic Concepts in Medicinal Chemistry

• Main Authors: Harrold, Marc W. (Author), Zavod, Robin M. (Author)
• Format: Book
• Language: English
• Published: Bethesda, Md. American Society of Health-System Pharmacists 2013
• Subjects: Chemistry, Pharmaceutical > Examination Question; Drug Interactions > Examination Question
• Online Access: Click Here to View Status and Holdings.
• Physical Description: x, 440 pages illustrations 26 cm
• Bibliography: Includes bibliographical references and index
• ISBN: 9781585282661; 1585282669

Medicinal chemistry is a complex topic. Written in an easy to follow and conversational style, Basic Concepts in Medicinal Chemistry focuses on the fundamental concepts that govern the discipline of medicinal chemistry as well as how and why these concepts are essential to therapeutic decisions. The book emphasizes functional group analysis and the basics of drug structure evaluation. In a systematic fashion, learn how to identify and evaluate the functional groups that comprise the structure of a drug molecule and their influences on solubility, absorption, acid/base character, binding interactions, and stereochemical orientation. Relevant Phase I and Phase II metabolic transformations are also discussed for each functional group.