Primary immunodeficiency diseases a molecular and genetic approach

• Other Authors: Ochs, Hans D 1936- (Editor), Smith, C. I. Edvard 1951- (Editor), Puck, Jennifer 1949- (Editor)
• Format: Book
• Language: English
• Published: Oxford Oxford University Press 2014
• Edition: Third Edition
• Subjects: Immunologic Deficiency Syndromes > genetics
• Online Access: Click Here to View Status and Holdings.
• Physical Description: xviii, 911 pages illustrations 29 cm
• Bibliography: Includes bibliographical references and index
• ISBN: 9780195389838; 0195389832

Primary immunodeficiency diseases, first recognized 60 years ago, are inherited disorders that affect human adaptive and innate immunity. In most cases, affected individuals experience recurrent infections, but they may also suffer from autoimmune diseases and malignancies. This third edition of Primary Immunodeficiency Diseases provides readers with the historic and scientific background, clinical presentations, immunologic characteristics, and the molecular/genetic underpinnings of this rapidly enlarging class of diseases. With up-to-date diagnostic tools and therapeutic options - from prophylactic anti-infective measures to hematopoietic stem cell transplantation and gene therapy - this volume will remain an authoritative resource on this increasingly important area