Antibiotics targets, mechanisms and resistance
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| Other Authors: | , , , |
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| Format: | Book |
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Weinheim
Wiley-VCH
2013
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| Subjects: | |
| Online Access: | Click Here to View Status and Holdings. |
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| LEADER | 00000n a2200000 a 4501 | ||
|---|---|---|---|
| 001 | wils-523940 | ||
| 020 | # | # | |a 9783527333059 (hbk.) |
| 020 | # | # | |a 3527333053 (hbk.) |
| 040 | # | # | |a UKMGB |b ITMB |
| 060 | 0 | 0 | |a QV 350 |
| 090 | 0 | 0 | |a QV 350 |b A6294 2014 |
| 245 | 0 | 0 | |a Antibiotics |b targets, mechanisms and resistance |c edited by Claudio O Gualerzi, Letizia Brandi, Attilio Fabbretti, and Cynthia L Pon |
| 260 | # | # | |a Weinheim |b Wiley-VCH |c 2013 |
| 300 | # | # | |a xxiv, 549 p. |b ill. (some col.) |c 26 cm |
| 504 | # | # | |a Includes bibliographical references and index |
| 505 | 1 | # | |a A chemist's survey of different antibiotic classes -- Antibacterial discovery: problems and possibilities -- Impact of microbial natural products on antibacterial drug discovery -- Antibiotics and resistance: a fatal attraction -- Fitness costs of antibiotic resistance -- Inhibitors of cell-wall synthesis -- Inhibitors of bacetrial cell partitioning -- The membrane as a novel target site for antibiotics to kill persisting bacterial pathogens -- Bacterial membrane, a key for controlling drug influx and efflux -- Interference with bacterial cell-to-cell chemical signaling in development of new anti-infectives -- Recent developments in inhibitors of bacterial type IIA topoisomerases -- Antibiotics targeting bacterial RNA polymerase -- Inhibitors targeting riboswitches and ribozymes -- Targeting ribonuclease P -- Involvement of ribosome biogenesis in antibiotic functions, acquired resistance, and future opportunities in drug discovery -- Aminoacyl-tRNA synthetase inhibitors -- Antibiotics targeting translation initiation in prokaryotes -- Inhibitors of bacterial elongation factor EF-Tu -- Aminoglycoside antibiotics: structural decoding of inhibitors targeting the ribosomal decoding A site -- Reptidyltransferase inhibitors of the bacterial ribosome -- Antibiotics inhibiting the translocation step of protein elongation on the ribosome -- Antibiotics at the ribosomal exit tunnel--selected structual aspects -- Targeting HSP70 to fight cancer and bad bugs: one and the same battle? |
| 650 | # | 0 | |a Drug Resistance, Bacterial |x pharmacology |
| 650 | # | 0 | |a Anti-Bacterial Agents |x pharmacology |
| 700 | 1 | # | |a Gualerzi, Claudio O. |d 1942- |
| 700 | # | # | |a Brandi, Letizia |
| 700 | # | # | |a Fabbretti, Attilio |
| 700 | # | # | |a Pon, Cynthia L. |d 1942- |
| 856 | 4 | 0 | |z Click Here to View Status and Holdings. |u https://opac.uitm.edu.my/opac/detailsPage/detailsHome.jsp?tid=523940 |
| 964 | # | # | |c BOK |d PH |
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ANTIBIOTICS CHALLENGES MECHANISMS OPPORTUNITIES