Host-fungus interactions methods and protocols

• Main Author: Brand, Alexandra C. (Author)
• Other Authors: MacCallum, Donna M.
• Format: Book
• Language: English
• Published: New York Humana Press 2012; ©2012
• Series: Methods in molecular biology (Clifton, NJ) v 845; Springer protocols v 845
• Subjects: Fungi > Laboratory Manuals; Fungi > Laboratory Manuals > pathogenicity; Candida albicans > Laboratory Manuals; Genetic Techniques > Laboratory Manuals; Host-Pathogen Interactions > Laboratory Manuals; Mycoses > Laboratory Manuals > pathogenicity
• Online Access: Click Here to View Status and Holdings.
• Physical Description: xvi, 597 pages some colour illustrations 27 cm
• Bibliography: Includes bibliographical references and index
• ISBN: 9781617795381; 1617795380 (hbk.)
• ISSN: 1064-3745

Microbiologists, medical mycologists, immunologists, and biochemists are increasingly working together to focus on the processes involved in the progression and treatment of fungal disease. Host-Fungus Interactions: Methods and Protocols is designed for research scientists who are involved in this work and interested in undertaking new or comparative studies of interactions between the mammalian host and clinically important fungal pathogens. Aiming to combine approaches for reverse genetics in pathogenic fungi with methods for their application in in vitro and in vivo models of disease, the book includes methods for the culture and genetic manipulation of the primary fungal pathogens and the opportunistic pathogens, as well as methods for investigating host-fungus interactions in model systems. Written in the highly successful Methods in Molecular Biology" series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and practical, Host-Fungus Interactions: Methods and Protocols describes available molecular methods and fungal infection models in great detail in order to encourage researchers to try new approaches to investigating host-fungus interactions with added levels of confidence.