Principles and practice of fertility preservation

• Other Authors: Donnez, Jacques (Editor), Kim, S. Samuel (Editor)
• Format: Book
• Language: English
• Published: Cambridge Cambridge University Press 2011
• Series: Cambridge medicine
• Subjects: Reproductive Techniques, Assisted; Cryopreservation > methods; Fertilization; Neoplasms > complications; Infertility > therapy; Ovary > transplantation
• Online Access: Click Here to View Status and Holdings.

"The specialty of fertility preservation offers patients with cancer, who are rendered infertile by chemo- and radiotherapy, the opportunity to realize their reproductive potential. This gold-standard publication defines the specialty. The full range of techniques and scientific concepts is cov...

Table of Contents:

• Machine generated contents note: Foreword; Preface; Part I. Introduction: 1. The evolution of ART; 2. The effect of chemotherapy and radiotherapy treatment for cancer on the reproductive system in humans; 3. Fertility preservation in non-cancer patients; Part II. Cancer Biology, Epidemiology and Treatment: 4. Basic cancer biology and immunology; 5. Breast cancer and fertility preservation: a view from oncology; 6. Breast cancer therapy and reproduction; 7. Pediatric cancer therapy and fertility; 8. Cancer epidemiology and environmental factors in children, adolescents and young adults; Part III. Reproductive Biology and Cryobiology: 9. Life and death in the germ line: apoptosis and the origins of DNA damage in human spermatozoa; 10. Molecular aspects of follicular development; 11. Fundamental cryobiology of reproductive cells and tissues: concepts and misconceptions; 12. Fundamental aspects of vitrification as a method of reproductive cell, tissue, and organ cryopreservation; Part IV. Fertility Preservation Strategies in the Male: 13. Hormonal suppression for fertility preservation in the male; 14. Cryopreservation of spermatozoa: old routine and new perspectives; 15. Transplantation of cryopreserved spermatogonia; 16. Fertility preservation strategies in males: cryopreservation and transplantation of testicular tissue; 17. Assisted reproductive techniques and donor sperm in cancer patients; Part V. Fertility Preservation Strategies in the Female: Medical/Surgical: 18. Use of GnRH agonists for prevention of chemotherapy-induced gonado-toxicity; 19. Ovarian transposition; 20. Fertility-saving surgery for cervical cancer; 21. Results of conservative management of ovarian malignant tumors; Part VI. Fertility Preservation Stategies in the Female: ART: 22. Embryo cryopreservation as a fertility preservation strategy; 23. Oocyte cryopreservation - slow freezing; 24. Cryopreservation of human oocytes and the evolution of vitrification technology for this purpose; 25. Cryopreservation and transplantation of isolated follicles; 26. ART and oocyte donation in cancer survivors; Part VII. Ovarian Cryopreservation and Transplantation: 27. General overview of ovarian cryobanking; 28. Ovarian tissue cryopreservation; 29. Ovarian tissue transplantation; 30. Whole ovary freezing; 31. Ovarian transplantation: whole ovary transplantation; Part VIII. In-Vitro Follicle Growth and Maturation: 32. Molecular and cellular integrity of cultured follicles; 33. In-vitro growth (IVG) systems for human oocytes: from primordial to maturation; 34. Contributions of ovarian stromal cells to follicle culture; 35. In-vitro maturation of GV oocytes; 36. Clinical potential of in-vitro maturation; Part IX. Future Technologies: 37. From pluripotent stem cells to germ cells; 38. Artificial ovary; 39. Predicting ovarian futures: the contribution of genetics; Part X. Ethical, Legal and Religious Issues with Fertility Preservation: 40. Psychological issues of cancer survivors; 41. Fertility preservation: ethical considerations; 42. Legal aspects of fertility preservation; 43. Christian ethics in fertility preservation; Index.