Gene transfer and the ethics of first-in-human research lost in translation

• Main Author: Kimmelman, Jonathan (Author)
• Format: Book
• Language: English
• Published: Cambridge, UK Cambridge University Press 2010
• Subjects: Gene Transfer Techniques > ethics; Human Experimentation > ethics; Public Policy
• Online Access: Click Here to View Status and Holdings.

"Human gene transfer is widely regarded as one of the most promising technologies for the treatment of a variety of disorders, but it presents practitioners with a variety of difficult ethical questions. Gene Transfer and the Ethics of First-in-Human Research examines the ethical and policy dim...

Table of Contents:

• Gene transfer lost in translation : an introduction
• What is gene transfer?
• Safety, values, and legitimacy : the protean nature of risk in translational trials
• Taming uncertainty : risk and gene transfer clinical research
• Succor or suckers? : evaluating the benefits of trial participation
• Looking backward : a model of value for translational trials
• Over the chasm : the initiation of first-in-human trials
• Tropic of cancers : gene transfer in resource-poor settings
• Great expectations and hard times : managing expectations in gene transfer
• Something in the sight adjusts itself.