Methods for the discovery and characterization of G protein-coupled receptors

• Other Authors: Stevens, Craig W. (Editor)
• Format: Book
• Language: English
• Published: New York Humana Press 2011
• Series: Neuromethods; Springer protocols
• Subjects: GTP-Binding Proteins; Receptors, G-Protein-Coupled
• Online Access: Click Here to View Status and Holdings.
• Physical Description: xiii, 428 pages illustrations 26 cm
• Bibliography: Includes bibliographical references and index
• ISBN: 9781617791789; 1617791784; 9781617791796 (e-ISBN); 1617791792 (e-ISBN)
• ISSN: 0893-2336

The goal of the characterization and discovery of G protein-coupled receptors, arguably the most important class of signaling molecules in humans and other vertebrates, has spawned numerous vital methodologies. In Methods for the Discovery and Characterization of G Protein-Coupled Receptors, experts in the field present the very latest on the methods and technology used to characterize and discover novel mechanisms of GPCRs which, in many cases, can be used directly to design experiments for the reader's particular GPCR of interest and their specific avenue of investigation. Divided into four convenient sections, this detailed volume covers GPCRs in the genome, trafficking of GPCRs, GPCRs on the membrane, as well as the regulation of these key receptors. Chapters also feature an important section called "Future Directions" which gives the reader an insight into advances soon to be realized in each area. Written for the popular Neuromethods series, this book contains the kind of detailed description and implementation advice that is crucial for getting optimal results. Authoritative and cutting-edge, Methods for the Discovery and Characterization of G Protein-Coupled Receptors serves as an ideal guide for scientists determined to further our knowledge of crucially important set of receptors