Computational genetics and genomics tools for understanding disease

• Other Authors: Peltz, Gary 1956- (Editor)
• Format: Book
• Language: English
• Published: Totowa, N.J. Humana Press 2005
• Subjects: Genomics > methods; Computational Biology; Disease Models, Animal; Mice, Transgenic > genetics
• Online Access: Click Here to View Status and Holdings.

Ultimately, the quality of the tools available for genetic analysis and experimental disease models will be assessed on the basis of whether they provide new information that generates novel treatments for human disease. In addition, the time frame in which genetic discoveries impact clinical practi...

Table of Contents:

• Computational biology: are we there yet? / Gary Peltz
• Statistical theory in QTL mapping / Benjamin Yakir, Anne Pisanté, and Ariel Darvasi
• Haplotype-based computational genetic analysis in mice / Jianmei Wang and Gary Peltz
• Haplotype structure of the mouse genome / Jianmei Wang ... [et al.]
• SNP discovery and genotyping: methods and applications / Jun Wang ... [et al.]
• Genetic and genomic approaches to complex lung disease using mouse models / Michael J. Holtzman, Edy Y. Kim, and Jeffrey D. Morton
• Murine models of osteoporosis / Robert F. Klein
• Murine models of substance and alcohol dependence: unraveling genetic complexities / Kim Cronise and John C. Crabbe
• Murine models of alcoholism: from QTL to gene / Chris Downing, Beth Bennett, and Thomas E. Johnson
• HLA polymorphism and disease susceptibility /
• Henry A. Erlich
• Asthma genetics: a case study / William Cookson.