Enzymes and Their Inhibition Drug Development

• Other Authors: Simons, Claire (Editor), Smith, H. John 1930- (Editor)
• Format: Book
• Language: English
• Published: London CRC Press 2005
• Series: CRC Enzyme Inhibitors Series
• Subjects: Enzyme inhibitors; Drug Design; Chemistry, pharmaceutical; Drug development; Chemistry pharmaceutical; Drug design
• Online Access: Click Here to View Status and Holdings.
• Physical Description: 308 pages illustrations 25 cm
• Bibliography: Includes bibliographical references and index
• ISBN: 9780415334020; 0415334020

Focusing on the development of enzyme inhibitors as therapeutic drugs, Enzymes and Their Inhibitors: Drug Development provides a concise overview of the chemistry of major types of enzymes and their inhibitors. The opening chapters introduce readers to the structure, functions, mechanisms, and kinetics of enzymes, including their use as disease markers, analytical reagents, and in industrial processes. Subsequent chapters discuss the different types of enzyme inhibitors and the principles involved in developing them into effective drugs. This outstanding text, also valuable as a professional reference, will be useful to all students of pharmacology and medicinal chemistry.