Clinical trials in infant nutrition methodology, statistics and ethical issues

• Other Authors: Perman, Jay A. (Editor), Rey, Jean (Editor)
• Format: Book
• Published: Washington, D.C, USA Lippincott-Raven 1998
• Series: Nestlé Nutrition workshop series v. 40
• Subjects: Infants > Congresses > Nutrition; Clinical trials > Congresses > Methodology
• Online Access: Click Here to View Status and Holdings.

 A comprehensive examination of the methodological, statistical and ethical problems of conducting clinical trials in paediatric nutrition. Randomized trials, meta-analyses and multi-centre studies - and the advantages and disadvantages of each - are discussed at length. Topics covered include the legislative framework of industrialized countries where trials are conducted; moral obligations in developing countries, particularly where ethics committees have not been established; regulations for formulating product claims that do not discourage breast feeding; and adherence to the ethics of protecting infants and children. The monograph seeks to give established and future investigators a better understanding of the most appropriate methods for clinical trials, and provides insight and inspiration to biostatisticians, ethics committee members, and the paediatric community.