Statins the HMG-CoA reductase inhibitors in perspective

• Other Authors: Packard, Christopher J. (Editor), Shepherd, J. 1944- (Editor), Gaw, Allan (Editor)
• Format: Book
• Language: English
• Published: London New York Independence, KY Martin Dunitz Distributed in the USA by Taylor & Francis 2004
• Edition: Second Editiion
• Subjects: Hyperlipidemia; Antilipemic agents
• Online Access: Click Here to View Status and Holdings.
• Physical Description: viii, 262 pages illustrations 26 cm
• Bibliography: Includes bibliographical references and index
• ISBN: 9781841842929; 1841842923

What is a statin? It is the most powerful lipid-lowering agent yet produced. Its main action is to lower the low-density lipoprotein (LDL) cholesterol level, thereby reducing the overall cholesterol level in the blood. In this new edition of this popular book, the authors examine the existing and emerging statins and their beneficial effectiveness in reducing serum cholesterol. New chapters cover combination therapy in lipid-lowering, new 'Megatrials' (HPS and PPP) and the PROSPER study. Also presented are the effects of statins on non-vascular conditions such as osteoporosis, cancer, dementia and diabetes