Anti-AIDS Drug Developmen challenges, strategies, and prospects

• Other Authors: Mohan, Prem (Editor), Baba, Masanori 1948- (Editor)
• Format: Book
• Language: English
• Published: Singapore Harwood Academic Publ. 1995
• Subjects: Anti-HIV Agents > chemistry
• Online Access: Click Here to View Status and Holdings.
• Physical Description: x, 298 pages illustrations 25 cm
• Bibliography: Includes bibliographical references and index.
• ISBN: 9783718656981; 3718656981

This text covers significant aspects that are involved in the search, design and development of potential anti-AIDS agents, with emphasis on areas related to drug development. These include enzyme inhibitors (reverse transcriptase, protease, glucosidase), inhibitors of gene expression (oligonucleotides), viral binding inhibitors (anionic compounds and CD4 mimetics) and various plant-derived products. A focus of this book is the medicinal chemistry of these classes of compounds. In addition, other areas that are pertinent to drug development are also addressed. These include HIV regulatory proteins, the development of anti-HIV-1 assays and resistance to anti-HIV-1 agents