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Vogelstein, Bert
Search Results - Vogelstein, Bert
Bert Vogelstein
Bert Vogelstein
(born 1949) is director of the Ludwig Center, Clayton Professor of Oncology and Pathology and a
Howard Hughes Medical Institute
investigator at The
Johns Hopkins
Medical School and
Sidney Kimmel Comprehensive Cancer Center
. A pioneer in the field of
cancer genomics
, his studies on colorectal cancers revealed that they result from the sequential accumulation of mutations in
oncogenes
and
tumor suppressor genes
. These studies now form the paradigm for modern cancer research and provided the basis for the notion of the somatic evolution of cancer.
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The genetic basis of human cancer
Published 2002
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Vogelstein, Bert
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Related Subjects
Cell Transformation, Neoplastic
Gene Expression
Mutagenesis
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genetics